The mimic epitopes ofMycobacterium tuberculosisscreened by phage display peptide library have serodiagnostic potential for tuberculosis
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identification of hitherto undefined b-cell epitopes by antibodies in the sera of vitiligo patients using phage-display peptide library
a random 12 mers phage library was used to screen a pool of immunoglo¬bulin fractions obtained from vitiligo patients. subsequent to panning experiments, a panel of affinity selected phage from vitiligo patients were obtained. this panel was tested using an elis a for their reactivity with pooled sera from patients and normal controls. among the 16 randomly selected clones, two of clones showed...
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The commercial availability of random peptide libraries displayed on the M13 phage is increasing their use forstudies on epitope identification, enzyme inhibitors, receptor ligands, etc. In this study two experimentswhere planned for selection of peptides. First with sheep antibodies, the positive selector was IgG, preparedon Protein G column from a pool of 11 sheeps immunized...
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BACKGROUND Precise determination of conformational epitopes of neutralizing antibodies represents a key step in the rational design of novel vaccines. A powerful experimental method to gain insights on the physical chemical nature of conformational epitopes is the selection of linear peptides that bind with high affinities to a monoclonal antibody of interest by phage display technology. Howeve...
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ژورنال
عنوان ژورنال: Pathogens and Disease
سال: 2016
ISSN: 2049-632X,2049-632X
DOI: 10.1093/femspd/ftw091